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Data can fight drug resistance

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Flu season is once again here and many South Africans will be turning to their trusted dose of antibiotics to resolve the outbreak as effectively as possible.  Despite this ongoing routine, South Africa is facing a huge problem.

A study led by Julia Gasson of the Western Cape Department of Health has revealed that local clinics are ignoring the guidelines on prescribing those antibiotics, and formal procedures are followed only 45% of the time.

Another global study, by the Center for Disease Dynamics, Economics & Policy (CDDEP), Princeton University, ETH Zurich and the University of Antwerp, analysed human antibiotic consumption in 76 countries and found it has increased worldwide from 11.3 to 15.7 defined daily doses (DDDs) per 1,000 inhabitants per day between 2000 and 2015.

The results of these actions are far-reaching. Antibiotics have begun to lose their effectiveness and we are developing a resistance to them. And the problem is more complicated than we had first thought. In one case, it was found that antibiotic resistant patients with infections such as E. coli and Klebsiella pneumonia had contracted a specific gene that had its origins on Chinese pig farms.

A crucial step in combatting antibiotic resistance lies in technological evolution

As a solution, scientists are now looking towards the field of bacterial genomics to tackle the global issue of antibiotic resistance. Genomics refers to the branch of molecular biology concerned with the structure, function, evolution, and mapping of our genes. This process can provide clarity around resistance mechanisms and even the evolution of various strains of disease. Today the process of genomics has also  become highly automated, which has been greatly accelerated through a combination of parallel processing and the advancement in data management processes.

Due these advancements, we are now entering a world of personalised medicine, whereby individual patients can be sequenced and comparative genomic analysis can provide vital information around the progression of resistant strains of disease. Within this context, technology plays a pivotal role in allowing bioinformaticians to work with and transfer data to clinicians in an efficient and timely manner.

NetApp is assisting to achieve this through our ONTAP Cloud storage software, which allows for the protection of genomic data whilst adding the flexibility to simplify the use of public cloud. We are currently seeing this process in action through our work with PetaGene – a team which originated from Cambridge University PHDs who required a novel approach to the problem of storing data associated genomics. Additionally, we are deploying the new and improved NetApp StorageGRID which now automates tamper proof retention of critical personal data. With an increased focus on data analytics, StorageGRID customers retain and manage an unlimited amount of rich media, which is particularly useful for the field of genomics.

The key benefits of applying technology to scientific research

Unlike generic data reduction techniques, there are a few key benefits of applying the process of data management to the pursuit of tackling antibiotic resistance:

o   Increased collaborative efficiency, with smaller more portable files transferable over the NetApp data fabric

o   Use less storage capacity and lower costs

o   Leverage the flexibility of the cloud. With the NetApp data fabric, files can be seamlessly and securely moved to and from the cloud

o   Maintain interoperability with existing workflows and formats

The field of genomics, underpinned by efficient data management, is the way forward in combatting the global issue of antibiotic resistance. This of course needs to be coupled with the necessary behavioural changes where prescription guidelines are followed to the tee. Within South Africa, a country marred by drug resistant infectious diseases ranging from HIV through to malaria, the need to simplify collaboration in genomics with improved data management has never been more crucial.

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Welcome to world of 2099

The world of 2099 will be unrecognisable from the world of today, but it can be predicted, says one visionary. ARTHUR GOLDSTUCK met him in Singapore.

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Futuristic structures tower over the landscape. Giant, alien-looking trees light up with dazzling colours amid the hundreds of plant species that grow up their trunks. Cosmetic stores sell their wares via public touch-screens, with products delivered instantly in drawers below the screens.

This is not a vision of the future. It is a sample of Singapore today. But it is also an inkling of the world we may all experience in the future.

Singapore was the venue, last week, of the World Cities Summit, where engineers, politicians, investors and visionaries rubbed shoulders as they talked about the strategies and policies that would enhance urban living in the future.

As part of the Summit, global payment technologies leader Mastercard hosted a small media briefing by one of Singapore’s leading thinkers about the future, Dr Damian Tan, managing director of Vickers Venture Partners. The company’s slogan “We invest in the extraordinary,” offers a small clue to Tan’s perspective.

“We look as far forward as 2099 because, as a venture capital firm, we invest in the long term,” he tells a group of journalists from Africa and the Middle East. “Companies explode in growth because there is value in the future. If there is no growth, they won’t explode.”

The big question that the Smart Cities Summit and Mastercard are trying to help answer is, what will cities look like in the year 2099? Tan can’t give an exact answer, but he offers a framework that helps one approach the question.

“If you want to look at 81 years into the future, and understand the change that will come, you need to double that amount and look into the past. That takes us to 1856. The difference between then and now is the difference you can expect between now and 2099.”

  •    Arthur Goldstuck is founder of World Wide Worx and editor-in-chief of Gadget.co.za. Follow him on Twitter on @art2gee and on YouTube

Use the page links below to continue reading about Tan’s visions.

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Win a Poster Heater with Gadget and Takealot.com

This winter Gadget and Takealot.com are giving away three Poster Heaters, which look like posters but become heaters when you plug them in.

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Three Gadget readers will each win a unit, valued at R550 each. To enter, follow @GadgetZA and @Takealot on Twitter and tell us on the @GadgetZA account how many Watts the heater consumes.

What’s the big deal about these heaters? Many of us are struggling to keep the balance between soaring electricity costs and the need to keep warm this winter.

However, the recently launched Poster Heater by EasyHeat and distributed in South Africa by Takealot.com is not only one of the most cost effective electric heaters currently on the market, it is also easy to setup and use.

As the name indicates, it is a poster similar to one you would hang on a wall. But, plug it in and it turns into a 300 Watt heater. The Poster Heater isn’t designed to heat hallways or large rooms, but rather smaller ones like a bedroom or a baby’s nursery or a dressing room.

It uses radiant heating, which means that it heats up in a couple of minutes and the heat is directed at the objects or people around it, quickly taking the chill out of the air and providing a comfortable ambient temperature.

The other advantage of radiant heating is that it doesn’t dry out the air like infrared or gas heaters. Users also don’t have to worry about their children or pets getting too close to it because, even though it gets hot, it can be touched.

To enter the competition follow the steps below:

Competition entry details:

1. Follow @GadgetZA and @Takealot on Twitter. (We will ONLY be accepting entries via Twitter, so please don’t enter through the comments section of this article.)

2. Tell us on Twitter, via @GadgetZA, mentioning @Takealot in your posting, how many Watts the Poster Heater consumes.

cleardot.gif3. The competition closes on 31 July 2018.

4. Winners will be notified via Twitter on 1 August and Takealot.com will be in touch to organise delivery.

5. The competition is only open to South African residents.

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